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Neuroscience Faculty and Their Research Interests

Louise Abbott
Morphological, biochemical, molecular and electrophysical changes in the central nervous system during development of neurological disorders in tottering mice.

Paul Brandt
Calcium homeostasis; calcium-dependent regulation of steroid receptors; exrpession of alpha integrins.

Gerald Bratton
Mechanisms by which lead enters the body and produces toxicity; nutritional influences on lead intoxication; heavy metal effects on reproductive function.

Antonio Cepeda-Benito
Associative and nonassociative drug tolerance with emphasis on morphine and nicotine.

Thomas Champney
Role of the pineal in seasonal and circadian rhythms; modulation of epilepsy and immune function by the pineal and its hormone, melatonin.

Wei-Jung Chen
Neurotoxicology, teratology, and developmental psychobiology.

Joan Coates
Congenital and inherited neurologic disorders; neurosurgery; brain tumors; degenerative myelopathy.

Sumana Datta
Development of the central nervous system in Drosophila melanogaster.

W. Les Dees
Molecular and physiological approaches for assessing neuroendocrine factors controlling and/or affecting the onset of female puberty.

Douglas P. Dohrman
Cellular mechanisms of drug addiction; alcohol and nicotine interactions; signal transduction.

David Earnest
Neurobiology of mammalian circadian rhythms and their regulation by light-dark signals.

Gerald Frye
Neuropharmacology of ethanol intoxication, tolerance, physical dependence and the fetal alcohol syndrome; GABA receptor adaptation in the regulation of neuronal excitability and in brain development; brain slice electrophysiology, primary neuronal culture and whole cell patch-clamp recording.

John Gelderd
Pathophysiological processes occurring following spinal cord injury; methods to promote neural regeneration.

Theresa Good
Development of in vitro models of neurodegeneration; spongiform encephalopathy; glaucoma.

James Grau
Learning and memory, spinal plasticity, and pain modulation.

William Griffith
Neurobiology of aging; cellular basis of epilepsy; brain slice electrophysiology and pharmacology; patch-clamp and single-channel recording of voltage and transmitter-activated currents.

Paul Harms
Reproductive physiology; endocrine regulation of pregnancy.

William Klemm
Brain mechanisms of alcohol intoxication; identification of bovine sex pheromones; effects of odor on electroencephalography; neuronal information processing.

Gladys Ko
circadian regulation of ion channels and neurotransmitter release in retina photoreceptors; synaptic plasticity in hippocampus.

 

Julian L. Leibowitz
Replication and gene expression of murine conronaviruses; molecular basis of pathogenesis of murine conronavirus-induced hepatitis and demyelinating disease.

Mary Meagher
Pain modulation; animal models of anxiety and mood disorders; learning and memory.

Rajesh Miranda
Roles of gonadal estradiol-17b and neurotrophins in the GABAergic neurons of the cerebral cortex; development of circuits involved in cognitive and affective behaviors.

Jack Nation
Neurochemical and neurobehavioral effects associated with environmental pollutants and drugs of abuse.

Cecil Reynolds
Neuropsychology of memory in children; relationship of affective disorder to neuropsychological processing deficits.

Ian Russell
Neural plasticity and mechanisms of learning and memory; recovery of visual function following cortical frontal eye-field lesions.

Farida Sohrabji
Role of gonadal hormones (estrogen) in the neurobiology of cognitive diseases; estrogen-neurotrophin regulation of adult and aging forebrain cholinergic circuits.

George Stoica
Mechanism(s) of retroviral-induced neurodegeneration.

Ralph Storts
Comparative neuropathology with particular interest in demyelinating diseases of the central and peripheral nervous systems.

Evelyn Tiffany-Castiglioni
Cellular mechanisms of neurotoxicity; functions of neuroglia; astroglial response to disease and trauma; cellular mechanisms of epilepsy.

Ronald B. Tjalkens
Research efforts focus on the role of heavy metals in Parkinson's Disease and the molecular regulation of inducible nitric oxide synthase in astrocytes in normal and pathophysiologic states.

Paul Wellman
Neurochemical basis for feeding and food intake.

Gregg B. Wells
Structure and function of neurotransmitter gated ion channels, including nicotinic acetylcholine, serotonin 5HT3, glycine, and GABAA receptors and cyclic nucleotide gated channels; role of protein structure in disease; clinical neuropathology.

Robert Wells
DNA structure; triplet repeats; human hereditary neuromuscular diseases.

C. Jane Welsh
Neurotropic viruses; autoimmune diseases of nervous system cerebrovascular endothelial cells; Theilers virus as a model of multiple schlerosis.

James West
Fetal alcohol syndrome and factors that influence the risk and severity of brain damage resulting from alcohol and other drugs of abuse during development.

Ursula H. Winzer-Serhan
Developmental neuropharmacology; effects of nicotine on the developing brain; gene regulation by nicotinic receptor activation.

Keith A. Young
The genetics, cell biology, neuropathology and treatment of brain diseases.

Mark Zoran
Developmental neurobiology; molecular determinants of synaptogenesis and synaptic specificity; mechanisms of synaptic plasticity.


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