Fall semesters BIOL 213-502 Molecular Cell Biology
Objectives: The purpose of this course is to provide a rigorous foundation in current molecular and cellular biology so that upper level life science courses will be more meaningful.
Spring semesters BIOL 613 Cell Biology
Objectives: This course is intended to give the student an advanced understanding of the molecular interactions and mechanisms underlying cell structure, function, and dynamics. In addition, students will learn the scientific methods used to investigate these processes. Both objectives will be achieved by lectures, readings, and critical analysis of seminal papers from the primary literature.
BIOL 681 Cilia/Flagella Journal Club
| Cilia/Flagella Journal Club 2011 Schedule Held 117 from 9:00-10:00am. |
| |
Date |
Who |
Paper |
Sept 5 |
No class |
|
Sept 12 |
Karl Aufderheide |
Talk: Cilia and their structures |
Sept 19 |
Sarah Herlihy |
Finetti F et al., Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat Cell Biol. 2009 Nov;11(11):1332-9. |
Sept 26 |
Robbie Schultz |
Mukhopadhyay S, et al., Sensory Signaling-Dependent Remodeling of Olfactory Cilia Architecture in C. elegans. Developmental Cell 14, 762–774, May 2008 |
Oct 3 |
Michelle Ramsey |
Sipe CW, Lu X. Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms Development. 2011 Aug;138(16):3441-9. |
Oct 10 |
David Silva |
Dishinger JF, et al., Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP. Nat Cell Biol. 2010 Jul;12(7):703-10. |
Oct 17 |
Robbie Schultz |
Moussaif M and Sze JY, Intraflagellar Transport/Hedgehog-Related Signaling
Components Couple Sensory Cilium Morphology and Serotonin Biosynthesis in Caenorhabditis elegans. The Journal of Neuroscience, April 1, 2009 • 29(13):4065– 4075 • 4065 |
Oct 24 |
Michelle Ramsey |
Seo JH, et al., Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet. 2011 Aug 25. [Epub ahead of print] |
Oct 31 |
Elizabeth Richey |
Suzanne R, et al., An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signaling without loss or malformation of cilia. Human Molecular Genetics, 2011, Vol. 20, No. 7 |
Nov 7 |
David Silva |
Ward HH, et al., A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1. Mol Biol Cell. 2011 Jul 20. [Epub ahead of print] |
Nov 14 |
Elizabeth Richey |
Tsao C-C, et al., Different Effects of Tetrahymena IFT172 Domains on Anterograde and Retrograde Intraflagellar Transport. Molecular Biology of the Cell
Vol. 19, 1450–1461, April 2008 |
Nov 21 |
Sarah Herlihy |
Wong SY, et al., Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 2009 Sep;15(9):1055-61. |
Nov 28 |
All |
Each will give a talk on his/her own work |
|