Ginger Carney's Lab Department of Biology
Research in Hongmin Qin’s lab uses simple eukaryotic microorganism Chlamydomonas to understand the assembly of cilium, an cellular organelle that has been implicated in a wide spectrum of human diseases (ciliopathies).
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Teaching

Fall semesters BIOL 213-502    Molecular Cell Biology

Objectives: The purpose of this course is to provide a rigorous foundation in current molecular and cellular biology so that upper level life science courses will be more meaningful.

Spring semesters BIOL 613 Cell Biology

Objectives: This course is intended to give the student an advanced understanding of the molecular interactions and mechanisms underlying cell structure, function, and dynamics. In addition, students will learn the scientific methods used to investigate these processes. Both objectives will be achieved by lectures, readings, and critical analysis of seminal papers from the primary literature.

BIOL 681 Cilia/Flagella Journal Club

Cilia/Flagella Journal Club 2011 Schedule                                Held 117 from 9:00-10:00am.
 

Date

Who

 Paper

Sept 5

No class

 

Sept 12

Karl Aufderheide

 Talk: Cilia and their structures

Sept 19

Sarah Herlihy

Finetti F et al., Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat Cell Biol. 2009 Nov;11(11):1332-9.

Sept 26

Robbie Schultz

Mukhopadhyay S, et al., Sensory Signaling-Dependent Remodeling of Olfactory Cilia Architecture in C. elegans. Developmental Cell 14, 762–774, May 2008

Oct 3

Michelle Ramsey

Sipe CW, Lu X. Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms Development. 2011 Aug;138(16):3441-9.

Oct 10

David Silva

Dishinger JF, et al., Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP.  Nat Cell Biol. 2010 Jul;12(7):703-10.

Oct 17

Robbie Schultz

Moussaif M and Sze JY, Intraflagellar Transport/Hedgehog-Related Signaling
Components Couple Sensory Cilium Morphology and Serotonin Biosynthesis in Caenorhabditis elegans. The Journal of Neuroscience, April 1, 2009 • 29(13):4065– 4075 • 4065

Oct 24

Michelle Ramsey

Seo JH, et al., Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet. 2011 Aug 25. [Epub ahead of print]

Oct 31

Elizabeth Richey

Suzanne R, et al., An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signaling without loss or malformation of cilia. Human Molecular Genetics, 2011, Vol. 20, No. 7

Nov 7

David Silva

Ward HH, et al., A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1. Mol Biol Cell. 2011 Jul 20. [Epub ahead of print]

Nov 14

Elizabeth Richey

Tsao C-C, et al., Different Effects of Tetrahymena IFT172 Domains on Anterograde and Retrograde Intraflagellar Transport. Molecular Biology of the Cell
Vol. 19, 1450–1461, April 2008

Nov 21

Sarah Herlihy

Wong SY, et al., Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 2009 Sep;15(9):1055-61.

Nov 28

All

Each will give a talk on his/her own work

 
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