RESEARCH

1. Fungal pathogenesis
---Cryptococcus neoformans
---Aspergillus fumigatus
2. Antifungal discovery

PUBLICATIONS

TEACHING

LAB MEMBERS

Xiaorong Lin (PI)
Srijana Upadhyay (research assoc.)   
Nadia Chacko (postdoc)
Xiuyun Tian (postdoc)
Linqi Wang (postdoc)
Rachana Gyawali(grad student)
Bing Zhai (grad student)
Dylan Foyle (undergrad)
Angelyn Hilton (undergrad)
Gail Pereira (undergrad)
Guadalupe Torres (undergrad)

LAB PHOTOS

Srijana Upadhyay Research Associate Contact information BSBW 435 3258 TAMU College Station, TX 77843-3258 Phone: 979-845-7259 Email: srijanaupadhyay@neo.tamu.edu

Biography

Srijana Upadhyay moved from Nepal to Texas in 2003. She obtained her Master’s degree in Vegetable Science and Bachelor degree in Agriculture from the Himachal Pradesh Krishi Vishvavidyalaya, India. After finishing her Master’s she worked in Nepal Agriculture Research council for a year where she was involved in tomato hybrid seed production program. There she helped to develop different inbred lines and hybrids of tomato. From 2002-2003 she worked as a vegetable breeder for Nepal SEAN Seed Company. From 2003 she had been working in the Department of Plant Pathology and Microbiology at Dr. Brian Shaw’s lab, where the research focused on fungal developmental biology. There she was mainly involved in the study of developmental biology and genetics of Aspergillus nidulans and evolution of asexual sporulation in filamentous fungi. After joining the Lin lab in 2010, Srijana is working on the discovery and characterization of novel developmentally regulated genes that are critical for fungal virulence.

Publications:

Zhai B, Zhu P, Foyle D, Upadhyay S, Idnurm A*, and Lin X*. (in press) Congenic strains of the filamentous form of Cryptococcus neoformans for studies of fungal morphogenesis and virulence. Infection and Immunity

B. D. Shaw, D.W. Chung, C. L. Wang; L. A. Quintanilla and S. Upadhyay. 2011.  A role for endocytic cycling in hyphal growth.  Fungal Biology 115: 541-546.

D.-W. Chung, C. Greenwald, S. Upadhyay, S. Ding, H. H. Wilkinson, D. J. Ebbole, and B. D. Shaw. 2011. acon-3, the Neurospora crassa ortholog of the developmental modifier, medA, complements the conidiation defect of the Aspergillus nidulans mutant. Fungal Genetics and Biology. 48: 370-376

S. Upadhyay, and B. D. Shaw. 2008. The Role of actin, fimbrin, and endocytosis in growth of hyphae in Aspergillus nidulans.  Molecular Microbiology 68: 690-705.

S. Upadhyay, and B. D. Shaw.  2006.  A phosphoglucose isomerase mutant in Aspergillus nidulans is defective in hyphal polarity and conidiation.  Fungal Genetics and Biology 43: 739-751. (Includes Cover Image)

B. D. Shaw and S. Upadhyay. 2005. Aspergillus nidulans swoK encodes an RNA binding protein that is important for cell polarity. Fungal Genetics and Biology 42: 862-872.