Faculty: Xiaorong Lin 2017-09-01T10:40:48+00:00
Xiaorong Lin

Xiaorong Lin

Professor

Fax: 979-845-2891
Email: xlin@bio.tamu.edu

Curriculum Vitae
Lin Lab Website

Office:
3258 TAMU
Biological Sciences Building West
Room 435D
979-845-7274

Lab:
Biological Sciences Building West
Room 435
979-845-7259

Joined the Department in 2008

  • B.S., 1996, Chemical Engineering, Dalian University of Technology, China
  • M.S., 1999, Chemical Engineering (Biochemical Engineering), Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China
  • Ph.D., 2003, Plant Biology (Fungal Genetics and Biology), University of Georgia, USA
  • Postdoctoral research, 2007, Molecular Genetics and Microbiology (Medical Mycology), Duke University Medical Center, USA

Associations:

  • Joint Associate Professor, Department of Microbiology and Immunology, Texas A&M Health Science Center
  • BWF Investigator in Pathogenesis of Infectious Disease
  • Member of Faculty of 1000

Awards:

  1. ICAAC Young Investigator Award, the American Society of Microbiology (ASM), 2009
  2. Teaching Excellence Award (SLATE), TAMU, 2009
  3. Eukaryotic Cell Outstanding Young Investigator Award, the American Society of Microbiology (ASM), 2009
  4. Teaching Excellence Award (SRATE), TAMU, 2011
  5. The Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Disease, 2013

Research in our laboratory focuses on medical mycology:  We study the molecular mechanisms of fungal pathogenesis and microbial communication and development.  We investigate novel drugs that have the potential to be used to treat fungal infections and we are interested in characterizing fungal molecules that are promising vaccine candidates.  The long term goal of our research is to seek better approaches for treating fungal diseases and to advance our knowledge of eukaryotic microbiology. Please check Lin Lab webpage for more details.

  1. Xu, X, Lin, J, Zhao, Y, Kirkman, E, So, YS, Bahn, YS et al.. Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation. PLoS Genet. 2017;13 (9):e1006982. doi: 10.1371/journal.pgen.1006982. PubMed PMID:28898238 PubMed Central PMC5595294.
  2. Gyawali, R, Zhao, Y, Lin, J, Fan, Y, Xu, X, Upadhyay, S et al.. Pheromone independent unisexual development in Cryptococcus neoformans. PLoS Genet. 2017;13 (5):e1006772. doi: 10.1371/journal.pgen.1006772. PubMed PMID:28467481 PubMed Central PMC5435349.
  3. Gyawali, R, Upadhyay, S, Way, J, Lin, X. A Family of Secretory Proteins Is Associated with Different Morphotypes in Cryptococcus neoformans. Appl. Environ. Microbiol. 2017;83 (5):. doi: 10.1128/AEM.02967-16. PubMed PMID:28039134 PubMed Central PMC5311391.
  4. Upadhyay, S, Xu, X, Lin, X. Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation. MBio. 2016;7 (6):. doi: 10.1128/mBio.01925-16. PubMed PMID:27879337 PubMed Central PMC5120144.
  5. Upadhyay, S, Xu, X, Lowry, D, Jackson, JC, Roberson, RW, Lin, X et al.. Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin. Cell Rep. 2016;14 (11):2511-8. doi: 10.1016/j.celrep.2016.02.059. PubMed PMID:26972005 PubMed Central PMC4805463.
  6. Xu, X, Zhao, Y, Kirkman, E, Lin, X. Secreted Acb1 Contributes to the Yeast-to-Hypha Transition in Cryptococcus neoformans. Appl. Environ. Microbiol. 2015;82 (4):1069-79. doi: 10.1128/AEM.03691-15. PubMed PMID:26637591 PubMed Central PMC4751841.
  7. Chacko, N, Zhao, Y, Yang, E, Wang, L, Cai, JJ, Lin, X et al.. The lncRNA RZE1 Controls Cryptococcal Morphological Transition. PLoS Genet. 2015;11 (11):e1005692. doi: 10.1371/journal.pgen.1005692. PubMed PMID:26588844 PubMed Central PMC4654512.
  8. Zhai, B, Wozniak, KL, Masso-Silva, J, Upadhyay, S, Hole, C, Rivera, A et al.. Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants. MBio. 2015;6 (5):e01433-15. doi: 10.1128/mBio.01433-15. PubMed PMID:26443458 PubMed Central PMC4611043.
  9. Wang, L, Lin, X. The morphotype heterogeneity in Cryptococcus neoformans. Curr. Opin. Microbiol. 2015;26 :60-4. doi: 10.1016/j.mib.2015.06.003. PubMed PMID:26094087 .
  10. Idnurm, A, Lin, X. Rising to the challenge of multiple Cryptococcus species and the diseases they cause. Fungal Genet. Biol. 2015;78 :1-6. doi: 10.1016/j.fgb.2015.05.002. PubMed PMID:25983191 PubMed Central PMC4461476.
Search PubMed

*Corresponding author