• B.S., 1972, University of Georgia, Chemistry, Zoology.
  • Ph.D., 1975, University of Georgia, Molecular Genetics.
  • Postdoctoral research: California Institute of Technology.

Joined the department in 1983.

Associations: Biological Clocks Program, Faculty of Molecular and Environmental Plant Sciences, Laboratory for Functional Genomics (Director).

Research Interests

My interests are evolutionarily broad and include animals, plants and fungi. A major focus of the lab is the genomic analysis of gene expression programs during plant gene expression programs, particularly during embryogenesis and seed development, and the underlying regulatory mechanisms required for the initiation and maintenance of these programs. This work has illustrated the combinatorial interactions of cis and trans -acting factors that result in specific gene regulatory events. We are also using genomics tools to study the interaction of the rice blast fungus, Magnaporthe grisea , with plant hosts; the circadian control of gene expression; and the development of the vertebrate retina. An additional focal area is the utilization of molecular and cellular approaches for crop improvement. As part of these research activities, we have developed or adapted high throughput genomics approaches to accelerate the gene discovery process and subsequent analysis of gene expression and function.

Patents

Chimeric Plant Genes Based on Upstream Regulatory Elements of Helianthinin T. Thomas, M. Bogue, M LeBrun and G. Freyssinet. USPTO Patent Nos. 5,824,865 (10/20/98), 5,859,325 (1/12/99), 5,905,186 (5/18/99).

Production of Gamma Linolenic Acid by a delta-6 -Desaturase T. Thomas, A.S Reddy, M. Nuccio and G. Freyssinet. USPTO Patent Nos. 5,552,306 (9/3/96); 5,614,393 (3/25/97); 5,663,068 (9/2/97); 5,789,220 (8/4/98).

Several other patents dealing with delta-6 -desaturase genes from various sources and with novel promoters we have developed have also been issued.

  1. Bennett, LD, Beremand, P, Thomas, TL, Bell-Pedersen, D. Circadian activation of the mitogen-activated protein kinase MAK-1 facilitates rhythms in clock-controlled genes in Neurospora crassa. Eukaryotic Cell. 2013;12 (1):59-69. doi: 10.1128/EC.00207-12. PubMed PMID:23125351 PubMed Central PMC3535850.
  2. Alvarado, VY, Tag, A, Thomas, TL. A cis regulatory element in the TAPNAC promoter directs tapetal gene expression. Plant Mol. Biol. 2011;75 (1-2):129-39. doi: 10.1007/s11103-010-9713-5. PubMed PMID:21107887 .
  3. Damaj, MB, Beremand, PD, Buenrostro-Nava, MT, Ivy, J, Kumpatla, SP, Jifon, J et al.. Isolating promoters of multigene family members from the polyploid sugarcane genome by PCR-based walking in BAC DNA. Genome. 2010;53 (10):840-7. doi: 10.1139/g10-064. PubMed PMID:20962891 .
  4. Smith, KM, Sancar, G, Dekhang, R, Sullivan, CM, Li, S, Tag, AG et al.. Transcription factors in light and circadian clock signaling networks revealed by genomewide mapping of direct targets for neurospora white collar complex. Eukaryotic Cell. 2010;9 (10):1549-56. doi: 10.1128/EC.00154-10. PubMed PMID:20675579 PubMed Central PMC2950426.
  5. Damaj, MB, Kumpatla, SP, Emani, C, Beremand, PD, Reddy, AS, Rathore, KS et al.. Sugarcane DIRIGENT and O-methyltransferase promoters confer stem-regulated gene expression in diverse monocots. Planta. 2010;231 (6):1439-58. doi: 10.1007/s00425-010-1138-5. PubMed PMID:20352262 .
  6. Damaj, MB, Beremand, PD, Buenrostro-Nava, MT, Riedel, B, Molina, JJ, Kumpatla, SP et al.. Reproducible RNA preparation from sugarcane and citrus for functional genomic applications. Int J Plant Genomics. 2009;2009 :765367. doi: 10.1155/2009/765367. PubMed PMID:20148085 PubMed Central PMC2817868.
  7. Mu, X, Fu, X, Beremand, PD, Thomas, TL, Klein, WH. Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc. Natl. Acad. Sci. U.S.A. 2008;105 (19):6942-7. doi: 10.1073/pnas.0802627105. PubMed PMID:18460603 PubMed Central PMC2383966.
  8. Karaganis, SP, Kumar, V, Beremand, PD, Bailey, MJ, Thomas, TL, Cassone, VM et al.. Circadian genomics of the chick pineal gland in vitro. BMC Genomics. 2008;9 :206. doi: 10.1186/1471-2164-9-206. PubMed PMID:18454867 PubMed Central PMC2405806.
  9. Roux, CM, Rolán, HG, Santos, RL, Beremand, PD, Thomas, TL, Adams, LG et al.. Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice. Cell. Microbiol. 2007;9 (7):1851-69. doi: 10.1111/j.1462-5822.2007.00922.x. PubMed PMID:17441987 .
  10. Menger, GJ, Allen, GC, Neuendorff, N, Nahm, SS, Thomas, TL, Cassone, VM et al.. Circadian profiling of the transcriptome in NIH/3T3 fibroblasts: comparison with rhythmic gene expression in SCN2.2 cells and the rat SCN. Physiol. Genomics. 2007;29 (3):280-9. doi: 10.1152/physiolgenomics.00199.2006. PubMed PMID:17284666 .
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Terry Thomas

Terry Thomas
Professor

3258 TAMU
College Station, TX 77843-3258

Office:
Biological Sciences Building East
Room 202B
979-845-0184

Lab:
Biological Sciences Building East
Room 201
979-845-0663

Fax: 979-847-8805
Email: terry@bio.tamu.edu

Curriculum Vitae