By bus:

From Mexico City's Terminal Norte, there are occasional Estrella Blanca second-class (unairconditioned, slow) buses to Calnali, about 5 hours, for about $100 pesos (US $10). There are also frequent Estrella Blanca buses to Huejutla and Molango, both of which stop in Molango (about 4 hours) where you can take a taxi into Calnali ($500 pesos, another 40 min). From the Mexico City airport, the easiest thing to do is to take a first-class airport bus to the Pachuca bus terminal ($170 pesos) and then catch one of the aforementioned buses north, although they often fill up in Mexico City and you may have to stand for a while. The bus passes right by CICHAZ before entering downtown Calnali; ask the bus driver to look out for the bougainvilleas on the left hand side after crossing the bridge before Calnali. If going by taxi, ask to be dropped off in Aguazarca.

From Tampico, there are several first-class ADO buses from the downtown ADO terminal to Huejutla several times a day (4 hours, about $200 pesos). From Huejutla, there are 1 or 2 combis (minibuses) to Huejutla and more frequent ones to Atlapexco. From there you can take a taxi to Calnali (about $500).

From Cd. Valles, take a bus to Tamazunchale and then ask for directions to the Huejutla bus stop; there are buses for about $50 pesos that take about an hour and run every half hour. Follow directions from Huejutla as above.

By car:

General tips for driving in Mexico

On rural roads, a left turn signal usually means "pass me", unless the car is slowing down,  and a right turn signal means "do not pass". When turning left, do not use your turn signal; slow down and stick your arm out the window to indicate a left turn.

Slow down for topes (speed bumps) through towns and small settled areas.

Be on the lookout for washouts and rockslides. Branches on the ground and red cloths on vegetation mean there's danger ahead, as do hazard lights on the vehicle in front of you.

Gas is available in several places in and around Calnali, sold out of 20-L jerrycans at a slight markup. The gas is fine, but it's cheaper and more convenient to try and fill up in Molango, Atlapexco, or Huejutla.

Directions from Tampico, College Station, Brownsville, McAllen, and points northeast: Take Hwy. XX west to Panuco, Veracruz.

At Pánuco, head south towards Tantoyuca, then bear southwest towards Huejutla.  Gas up in Huejutla, as it’s the last real gas station before Calnali. It’s slightly over an hour to Calnali.  Follow signs out of Huejutla towards Mexico City and Pachuca . Right after leaving the built-up area of Huejutla, turn left towards Atlapexco. Immediately before Atlapexco, turn right onto bypass road towards Yahualica.  Keep going straight through Tlalchiyahualica and Mecatlan (do not turn uphill towards Yahualica).  You’ll go over a bridge after Mecatlan, and the kilometer markers now count down to the Calnali turnoff.  There are frequent rockslides on this road, so be careful.  Pass the town of Calnali , on your right, and both turnoffs for Calnali/centro.  CICHAZ is on your right about 100 m after the second turnoff.

By car from Cd. Valles, S. L. P., Monterrey , Laredo , and points northwest:

Drive south on federal Highway 85 to Tamazunchale; right after the bridge, turn left towards S. Felipe Orizatlán. Bypass S. Felipe Orizatlán, then turn right towards Mexico City/Pachuca before you enter Huejutla.  The bypass road will cross Hwy. 105; keep going straight towards Atlapexco and follow directions above.

By car from Tuxpan, Veracruz port, and points southeast:

From Álamo , Veracruz , follow signs to Chicontepec.  At Benito Juárez, keep going straight on towards Atlapexco and Huautla (do not turn towards Chicontepec). The last gas station is right before Atlapexco.  Keep going straight towards Atlapexco, and stay on the bypass road to the right of the town of Atlapexco .  Immediately after passing the town, turn left towards Yahualica and follow directions as above.

By car from Mexico City , Pachuca , and points south and southwest:

Take Hwy. 105 north through Zacualtipán. There can be dense fog from this point on.  Gas up in Molango.  Right before Ixtlahuaco, turn east (downhill) towards Calnali. After about 20-30 min, you’ll cross a bridge over the Río Calnali (Calnali-mid). CICHAZ will be on your left next to the Vidrios y Aluminio sign.  

By donkey from Pochula:

The donkey knows where to go.