• Cell biology
  • Cell proliferation
  • Cell chemotaxis
  • Signal transduction
• The mechanism of polyphosphate regulating Dictyotelium discoideum proliferation

Publications:

1. Tang, Y., Wu, Y., Herlihy, S. E., Brito-Aleman, F. J., Ting, J. H., Janetopoulos, C., & Gomer, R. H. (2018). An Autocrine Proliferation Repressor Regulates Dictyostelium discoideum Proliferation and Chemorepulsion Using the G Protein-Coupled Receptor GrlH. mBio, 9(1), e02443-17. doi:10.1128/mBio.02443-17
2. Suess, Patrick M., Yu Tang, and Richard H. Gomer. “The putative G protein-coupled receptor GrlD mediates extracellular polyphosphate sensing in Dictyostelium discoideum.” Molecular biology of the cell (2019): mbc-E18.
3.  Consalvo, K.M., Rijal, R., Tang, Y., Kirolos, S.A., Smith, M.R., and Gomer, R.H. Extracellular signaling in Dictyostelium. The International Journal of Developmental Biology (2019) In Press
4. Herlihy, Sarah E., Yu Tang, Jonathan E. Phillips, and Richard H. Gomer. “Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl‐peptidase IV.” Protein Science 26, no. 3 (2017): 578-585.
5. Tang, Yu, Yuantai Wu, Sarah E. Herlihy, Francisco J. Brito-Aleman, Jose H. Ting, Chris Janetopoulos, and Richard H. Gomer. “An Autocrine Proliferation Repressor Regulates Dictyostelium discoideum Proliferation and Chemorepulsion Using the G Protein-Coupled Receptor GrlH.” mBio 9, no. 1 (2018): e02443-17.

Presentations:

1. Poster, ILSB, SPRC event, 9-29-2018. A signal transduction pathway for an autocrine signal that inhibits cell proliferation
2. An autocrine proliferation repressor regulates Dictyostelium proliferation and chemorepulsion through a G protein-coupled receptor
   ILSB 1105, September 2017, poster