
Matthias Koch
Office:
409 BSBW
Lab:
401 BSBW
Joined the Department in 2022
- M.Sc., Physics, University of Freiburg. 2010
- Ph.D., Biophysics. 2015
- Postdoctoral research, Princeton University. 2015-2022
- Padron, GC, Shuppara, AM, Sharma, A, Koch, MD, Palalay, JS, Radin, JN et al.. Shear rate sensitizes bacterial pathogens to H2O2 stress. Proc Natl Acad Sci U S A. 2023;120 (11):e2216774120. doi: 10.1073/pnas.2216774120. PubMed PMID:36888662 .
- Koch, MD, Shaevitz, JW. Art Ashkin and the Origins of Optical Trapping and Particle Manipulation. Methods Mol Biol. 2022;2478 :11-22. doi: 10.1007/978-1-0716-2229-2_2. PubMed PMID:36063316 .
- Koch, MD, Black, ME, Han, E, Shaevitz, JW, Gitai, Z. Pseudomonas aeruginosa distinguishes surfaces by stiffness using retraction of type IV pili. Proc Natl Acad Sci U S A. 2022;119 (20):e2119434119. doi: 10.1073/pnas.2119434119. PubMed PMID:35561220 PubMed Central PMC9171759.
- Koch, MD, Fei, C, Wingreen, NS, Shaevitz, JW, Gitai, Z. Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili. Proc Natl Acad Sci U S A. 2021;118 (8):. doi: 10.1073/pnas.2014926118. PubMed PMID:33593905 PubMed Central PMC7923367.
- Scheffler, RJ, Sugimoto, Y, Bratton, BP, Ellison, CK, Koch, MD, Donia, MS et al.. Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule. J Biol Chem. 2021;296 :100279. doi: 10.1016/j.jbc.2021.100279. PubMed PMID:33450229 PubMed Central PMC7949062.
- Simsek, AN, Braeutigam, A, Koch, MD, Shaevitz, JW, Huang, Y, Gompper, G et al.. Substrate-rigidity dependent migration of an idealized twitching bacterium. Soft Matter. 2019;15 (30):6224-6236. doi: 10.1039/c9sm00541b. PubMed PMID:31334524 .
- Sanfilippo, JE, Lorestani, A, Koch, MD, Bratton, BP, Siryaporn, A, Stone, HA et al.. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019;4 (8):1274-1281. doi: 10.1038/s41564-019-0455-0. PubMed PMID:31086313 PubMed Central PMC6656604.
- Roth, J, Koch, MD, Rohrbach, A. Dynamics of a Protein Chain Motor Driving Helical Bacteria under Stress. Biophys J. 2018;114 (8):1955-1969. doi: 10.1016/j.bpj.2018.02.043. PubMed PMID:29694872 PubMed Central PMC5937200.
- Koch, MD, Rohrbach, A. Label-free Imaging and Bending Analysis of Microtubules by ROCS Microscopy and Optical Trapping. Biophys J. 2018;114 (1):168-177. doi: 10.1016/j.bpj.2017.10.036. PubMed PMID:29320684 PubMed Central PMC5773756.
- Sabass, B, Koch, MD, Liu, G, Stone, HA, Shaevitz, JW. Force generation by groups of migrating bacteria. Proc Natl Acad Sci U S A. 2017;114 (28):7266-7271. doi: 10.1073/pnas.1621469114. PubMed PMID:28655845 PubMed Central PMC5514709.